Endocrine Abstracts

With increasing prevalence of type 2 diabetes in India, macrovascular complications are also on the rise. We undertook a retrospective study to evaluate the metabolic profile of type 2 diabetes patients undergoing coronary artery bypass grafting (CABG) at our centre. Clinical data on 672 consecutive patients undergoing elective CABG was included from the hospital data base after informed consent and ethics committee approval. Mean age of the patients was 49.7±9.5 years; 5...

Women with polycystic ovary syndrome (PCOS) have twice the risk for metabolic syndrome (MetS) compared to women from the general population. Mothers and sisters of affected women also have an increased prevalence of MetS. We undertook this study to evaluate whether these abnormalities are also present in brothers’ of affected women.Design and setting: A total of 59 brothers (age ≥18 and ≤40 years) of women with PCOS and 59 healthy men (o...

Background and aims: In diabetic pregnancy, neonatal hypoglycemia (NH) is usually attributed to insufficient regulation of maternal glycemic control. Recent data suggest that maternal BMI could have an influence on NH. The objective of this study was to determine whether an association exists between maternal prepregnancy BMI and occurrence of NH among infants born to women with gestational diabetes mellitus (GDM).Materials and methods: This was a retros...

Background and aims: Proper assessment of long-term safety of newer antidiabetic agents (ADAs) is of prime importance as diabetes is a chronic disease requiring life-long management. The purpose of this analysis was to assess the safety of vildagliptin as monotherapy or as an add-on therapy to already existing ADAs (vildagliptin group) compared to non-vildagliptin group.Materials and methods: Nine hundred and eighty-three patients in vildagliptin group a...